Homatropine hydrobromide (AK-Homatropine, Homatrine, Isopto Homatropine)

Category:

• Nervous system

Description:

• Mydriatic, cycloplegic

Indications:

• Uveitis

• Iritis

• Mydriatic

• Cycloplegic for refraction

Contraindications:

• Adhesions between the iris and lens

• Primary glaucoma, narrow anterior chamber angle

Precautions:

• Pregnancy category C; compatible with breastfeeding

• Elderly, small children, and infants

Adverse Reactions (Side Effects):

• CNS: confusion fever, headache, somnolence, visual hallucinations

• CV: tachycardia, vasodilation

• EENT: blurred vision, edema, increased intraocular pressure, photophobia

• GI: abdominal distension in infants, decreased GI motility, dry mouth

• GU: urinary retention

• SKIN: dry skin, rash

Dosage:

Administered as an ophthalmic solution

• Adult and Child: 

  • INSTILL 1 drop; repeat in 5-10 minutes for refraction or every 3-4 hours for uveitis

  • patients with heavily pigmented irides may require larger doses

  • use only 2% strength in children and compress the lacrimal sac for several minutes following administration